Estrogen deficiency during menopause can contribute to alterations in cellular metabolism, fat distribution, and body composition, predisposing women to stress-based diabetic obesity and associated metabolic complications. Understanding the complex interplay between hormonal, metabolic, and psychosocial factors is essential for addressing the unique challenges faced by women during the menopausal transition and optimizing metabolic health and well-being… Read More »

Estrogen plays a crucial role in maintaining calcium homeostasis by regulating calcium absorption, reabsorption, secretion, and bone turnover. Dysfunction or deficiency of estrogen can disrupt these processes, leading to calcium imbalances and associated health complications such as osteoporosis… Read More »

Estrogen and parathyroid hormone interact in complex ways to regulate calcium metabolism, bone turnover, and hormonal balance in the body. Further research is needed to fully elucidate the molecular mechanisms underlying their interactions and their implications for health and disease… Read More »

Estrogen exerts potent inhibitory effects on osteoclast activity by targeting multiple stages of osteoclast development and function. By suppressing osteoclast formation, promoting osteoclast apoptosis, disrupting osteoclast function, and modulating RANKL/OPG signaling, estrogen helps maintain bone mass and prevent excessive bone loss…. Read More »

Estrogen exerts pleiotropic effects on osteoblasts through direct and indirect mechanisms, ultimately promoting bone formation and maintenance. Dysfunction or deficiency of estrogen can lead to impaired osteoblast function, contributing to conditions such as osteoporosis and increased fracture risk… Read More »

© 2024 Medcoi LLC, all rights reserved.
go to top