Aybintio (abaloparatide)
Aybintio is a prescription medicine used to treat osteoporosis in postmenopausal women at high risk…
Estrogen plays a crucial role in maintaining calcium homeostasis by regulating calcium absorption, reabsorption, secretion, and bone turnover. Dysfunction or deficiency of estrogen can disrupt these processes, leading to calcium imbalances and associated health complications such as osteoporosis… Read More »
Estrogen exerts potent inhibitory effects on osteoclast activity by targeting multiple stages of osteoclast development and function. By suppressing osteoclast formation, promoting osteoclast apoptosis, disrupting osteoclast function, and modulating RANKL/OPG signaling, estrogen helps maintain bone mass and prevent excessive bone loss…. Read More »
Estrogen exerts pleiotropic effects on osteoblasts through direct and indirect mechanisms, ultimately promoting bone formation and maintenance. Dysfunction or deficiency of estrogen can lead to impaired osteoblast function, contributing to conditions such as osteoporosis and increased fracture risk… Read More »