What medications require caution or avoidance during pregnancy?

It’s essential for women to consult with their healthcare providers about any medications, especially during pregnancy. The safety of medications can vary, and the decision to avoid or continue a specific medication depends on individual health conditions. Here are 10 medications that might require caution or avoidance during pregnancy:

1. Isotretinoin (Accutane):
   • Used for severe acne, it can cause serious birth defects if taken during pregnancy.
2. Thalidomide:
   • Historically used for morning sickness but withdrawn due to causing birth defects.
3. Warfarin:
   • An anticoagulant that can pose risks to the developing fetus.
4. Methotrexate:
   • Used for certain autoimmune conditions, it can harm the developing fetus.
5. Angiotensin-Converting Enzyme (ACE) Inhibitors:
   • Medications like enalapril and lisinopril, used for hypertension, can be harmful during pregnancy.
6. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs):
   • Including ibuprofen and naproxen, especially during the third trimester.
7. Tetracycline Antibiotics:
   • Can affect fetal bone development and discolor teeth.
8. Fluconazole:
   • High doses for yeast infections might be associated with birth defects.
9. Lithium:
   • Used for bipolar disorder, it may pose risks to the developing fetus.
10. Valproic Acid (Depakote):
    • Used for seizures and mood disorders, it has been associated with birth defects.

It’s crucial to consult with a healthcare professional for personalized advice. In some cases, the benefits of continuing medication may outweigh the potential risks, and alternatives or adjustments can be considered. Never discontinue or change medication without consulting a healthcare provider, especially during pregnancy!!

Verified by: Dr.Diab (December 19, 2023)

Citation: Dr.Diab. (December 19, 2023). What Medications require caution or avoidance during pregnancy. Medcoi Journal of Medicine, 2(2). urn:medcoi:article22689.