The lowest effective dose of estrogen for menopause is typically around 0.3 mg of oral conjugated estrogens or 0.5 mcg of transdermal estradiol. Higher doses of estrogen may be prescribed depending on the severity of symptoms and individual response to treatment. However, doses exceeding 1-2 mg of oral conjugated estrogens or 100-200 mcg of transdermal estradiol are less commonly used due to increased risks of adverse effects…. Read More »